Digestion starts through the sight, thought, or smell of food. Once the mind anticipates an just arrive meal, the vagus nerve sends a blog post to the stomach resulting in the relax of acetylcholine. The binding of acetylcholine to G cell in the stomach start the secretion of gastrin and, in combination with acetylcholine andhistamine, stimulates parietal cell in the gastric glands the the stomach body to begin secreting hydrochloric mountain (HCl).

You are watching: Which of the following statements about the role of hydrochloric acid (hcl) is false?

Acid in the stomach serves number of purposes however is mostly associated with degrading proteins and also polysaccharides for this reason they can cross the intestinal epithelium. Around 2 together of HCl is produced daily. The pH level in the stomach arrays from 1.5 come 3, depending upon factors such together food intake, stress, and also medications or supplements.1An boost in HCl and also decreasing pH level also signal gastric motility to rotate on to relocate the partially digested bolus the food along and assist kill bacteria generally ingested v food. The pH the the stomach is regulation by a an adverse feedback loop by antral D cell that relax somatostatin which inhibits the relax of gastrin.2As food moves out of the stomach, the H+ concentration rises which likewise serves to inhibit HCl secretion.1

Hydrochloric mountain contributes to protein digestion by providing H+ which activates pepsinogen, the precursor come pepsin. Pepsinogen is secreted by chief cell in the gastric glands of the body and antrum the the stomach. Protein are diminished to fragments of various sizes, called peptides, or amino acids, by pepsin so they can ultimately be took in in the tiny intestine. This rise in peptides and amino acids, in addition to distention from food, more increases HCl secretion. Without adequate HCl secretion, larger fragments of proteins get in the small intestine and may weaken the efficacy of cradle processes. Tension may affect HCl secretion as enhanced parasympathetic task to the stomach’s enteric nervous device stimulates the release of acetylcholine, gastrin, and also histamine.1.


Widmaier EP, Raff H, Strang KT.Vander"s person Physiology: the instrument of human body Function. Boston: McGraw-Hill; 2006. Rundown of acid Secretion. Merck Manuals expert Edition. https://www.merckmanuals.com/professional/gastrointestinal-disorders/gastritis-and-peptic-ulcer-disease/overview-of-acid-secretion. Accessed June 27, 2016.

Last Updated:

Related Articles

You might additionally like...


High sheep Probiotics: Is an ext Always Better?

With good gut wellness being in ~ the head of medicine, would it be realistic to think of adding even an ext microorganisms come the cradle tract?

Read an ext

What to suppose When beginning an elemental Diet

The an easy premise the an elemental diet is offering nutrition in an conveniently absorbable form, including all macronutrients: carbohydrates, fats, and protein.

Read more

A Closer Look at Zinc-Carnosine

The usage of zinc-carnosine has been clinically studied because that over 20 years, within its beginning dating ago to Japan.

Read an ext

how Ginger and also Artichoke job-related

Ginger and also artichoke have been a clip of traditional medicine because that centuries.

Read more

digestive Enzymes: Amylase, Protease, and Lipase

The ide of digestive enzymes is reasonably easy come understand, yet when delving into the details the is advantageous to take a step back and understand what the myriad of easily accessible enzymes room actually performing in ~ the body.

Read much more

V clean EPs 7630® Original

V clear EPs 7630™ is an top respiratory treatment containing a proprietary, homeopathic ready of Pelargonium sidoides extract i m sorry addresses the underlying reason of symptoms to help speed recovery, and shorten the expression of top respiratory irritations.

V clean EPs 7630® Cherry

V clean EPs 7630® is an upper respiratory therapy containing a proprietary, homeopathic ready of Pelargonium sidoides extract i beg your pardon addresses the underlying reason of symptoms to assist speed recovery, and shorten the expression of top respiratory irritations.

See more: Can I Use Hair Removal Cream On My Balls ? Can I Use Nair On My Balls

watch Product Details

Vitaline® CoQ10 (400 mg)

Supports heart and brain health.*

view Product Details

Probiotic Pearls™

Probiotic Pearls™ room a mix of energetic cultures including Lactobacillus and also Bifidobacterium for healthy and balanced gastrointestinal and also immune function in basic to gulp down capsule.*


Esberitox™ consists of immune-supporting combination of Echinacea, baptisia, and also thuja.* The subject of numerous clinical trials and also studies, Esberitox is among the most trusted and also recommended Echinacea products available.