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New Data Confirms solid and Long-Lasting defense of Johnson & Johnson COVID-19 Vaccine
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Note: This release corresponds to American Diabetes association (ADA) abstract 268-OR

larger adults have the highest possible prevalence of diabetes of any kind of age group, with an ext than 25 percent the U.S. Adult aged 65 years and older living through diabetes.

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<1> The aging the the all at once U.S. Population is acknowledged as a driver of the diabetes epidemic.<2> kind 2 diabetes comprises 90 to 95 percent of civilization with diabetes and also if left uncontrolled have the right to lead to serious complications.<1>

The percent the patients getting to the A1C goal level of less than 7.0 percent: 15.6 percent (CI 7.2, 24.0) and also 21.7 percent (CI 13.0, 30.3) Body weight reduction: -2.3 percent (CI -3.1, -1.6) and -3.2 percent (CI -4.0, -2.4) Fasting plasma glucose reduction: -21.4 mg/dL (CI -28.5, -14.2) and -23.4 mg/dL (CI -30.6, -16.2) Systolic blood push reduction: -5.8 mm Hg (CI -8.0, -3.5 and -7.5 mm Hg (CI -9.8, -5.2) increased levels the HDL-C (high-density lipoprotein cholesterol): 3.6 percent (CI 0.4, 6.9) and 4.8 percent (CI 1.5, 8.1)

For an ext details about the study, visit the American Diabetes Association scientific Sessions website and also search digital abstracts because that presentation number 268-OR.

infections and also increased urination. These certain adverse events were usually mild to moderate in

intensity and infrequently led to discontinuation in step 3 studies.

About type 2 Diabetes

An estimated 371 million an international are living through diabetes<4> and approximately 25.8 million human being have diabetes in the unified States.<5> type 2 diabetes comprises 90 percent of world with diabetes,<6> i beg your pardon is chronic and affects the body"s capability to metabolize street (glucose), and is characterized by the inability of pancreatic beta cell role to keep up v the body"s demand for insulin.

Nearly fifty percent of adults with kind 2 diabetes execute not attain recommended levels of glucose control, and if left uncontrolled, type 2 diabetes have the right to lead to significant complications.<7>,<8>,<9> boosted glycemic control has to be demonstrated to alleviate the onset and progression of these complications. <10>

IMPORTANT security INFORMATION

You may be at greater risk that dehydration if you:

Tell her doctor around all the drugs you take,including prescription and non-prescription medicines, vitamins, and also herbal supplements.

asking your doctor or pharmacist because that a perform of these medications if you are not sure if your medicine is detailed above. know the drugs you take. Save a list of them and also show that to your doctor and pharmacist as soon as you acquire a new medicine.

Signs and symptoms of low blood sugar may include:

speak to your physician for clinical advice about side effects. You might report side results to FDA in ~ 1-800-FDA-1088.

friend may also report side impacts to Janssen scientific Affairs, llc at 1-800-526-7736.

Please watch the fullPrescribing InformationandMedication Guide.

Trademarks room those that their particular owners.

About Janssen research study & Development, LLCAt Janssen, we are dedicated to addressing and solving several of the most vital unmet medical needs of ours time in oncology, immunology, neuroscience, contagious diseases and also vaccines, and cardiovascular and also metabolic diseases. Moved by our commitment to patients, we build innovative products, services and also healthcare solutions to aid people throughout the world. Janssen study & Development, LLC and also Janssen scientific Affairs, gmbh are part of the Janssen pharmaceutical Companies. You re welcome visit http://www.janssenrnd.com for an ext information.

This press release includes "forward-looking statements" as defined in the private Securities Litigation reform Act that 1995. The reader is cautioned not to rely on these forward-looking statements. This statements are based upon current expectations of future events.If underlying assumptions prove inaccurate or unknown risks or unpredictabilities materialize, really results might vary materially native the expectations and projections of Janssen study & Development, LLC, any type of of the various other Janssen Pharmaceutical suppliers and/or Johnson & Johnson.Risks and uncertainties include, yet are not limited to: financial factors, such as attention rate and also currency exchange price fluctuations; competition, including technological advances, brand-new products and also patents attained by competitors; obstacles inherent in brand-new product development, consisting of obtaining regulation approvals; challenges to patents; changes in behavior and also spending fads or financial distress that purchasers the health treatment products and services; transforms to governmental laws and also regulations and also domestic and foreign health treatment reforms; general industry conditions including trends towards health care cost containment; and increased scrutiny the the health treatment industry by government agencies. A further list and description of these risks, uncertainties and other components can be discovered in Johnson & Johnson’s yearly Report on form 10-K for the fiscal year finished December 29, 2013, consisting of in exhibition 99 thereto, and also our succeeding filings with the Securities and also Exchange Commission. Duplicates of these filings are easily accessible online in ~ www.sec.gov, www.juniorg8.com or on inquiry from Johnson & Johnson. None of the Janssen Pharmaceutical service providers nor Johnson & Johnson undertakes to update any kind of forward-looking statements together a an outcome of brand-new information or future occasions or developments.

###

References

<1> Centers for condition Control and also Prevention. National diabetes reality sheet: national estimates and general information on diabetes and prediabetes in the united States, 2011. Atlanta, GA: U.S. Department of Health and Human Services, Centers for condition Control and Prevention, 2011.

<2> American Diabetes combination .Older Adults. Obtainable at: www.diabetes.org/in-my-community/awareness-programs/older-adults/.

<3> American Diabetes Association. Living with diabetes: A1C. Available at: http://www.diabetes.org/living-with-diabetes/treatment-and-care/blood-glucose-control/a1c/?keymatch=A1c.

<4> international Diabetes Federation, Diabetes Atlas 5th Edition 2012 Update, new estimates because that 2012 that diabetes prevalence, mortality, and healthcare expenditures. Available at: http://www.idf.org/sites/default/files/IDF%20Diabetes%20Atlas%205th%20Edition%202012%20Update_1.ppt.

<5> Centers for an illness Control and also Prevention. Nationwide diabetes reality sheet: national estimates and also general information on diabetes and also prediabetes in the joined States, 2011. Atlanta, GA: U.S. Department of Health and also Human Services, Centers for condition Control and also Prevention, 2011.

<6> Definition, diagnosis and also classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Geneva, world Health Organization, 1999 (WHO/NCD/NCS/99.2).

<7> Bailey CJ. Renal glucose reabsorption inhibitors come treat diabetes. Fads Pharmacol Sci. 2011;32(2):63-71.

<8> Casagrande SS, Fradkin JE, Saydah SH, Rust KF, Cowie CC. The prevalence of meeting A1C, blood pressure, and LDL goals amongst people with diabetes, 1988–2010. Diabetes Care. 2013 Feb 15. Epub ahead of print.

<9> civilization Health Organization, Media Centre, Diabetes, reality sheet Number 312. Accessible at: http://www.who.int/mediacentre/factsheets/fs312/en/. Accessed April 1, 2013.

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<10> Centers for disease Control and also Prevention. National diabetes truth sheet: national estimates and general information on diabetes and also prediabetes in the united States, 2011. Atlanta, GA: U.S. Room of Health and also Human Services, Centers for an illness Control and also Prevention, 2011.